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PMID: 18796312 View source Ballatori N, et al

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2000;278:E86876

Apart from the unknown side effect profile for people who are pregnant or breastfeeding, the biggest safety issue with TMG supplementation is the risk of elevated cholesterol.32 But the risk seems to present itself only with doses exceeding 4g per day.9 The label-recommended doses of our top-recommended TMG supplements are significantly lower than 4g, so you ought to be fine taking any of them unless you already have a high or borderline-high lipid profile